Confocal Microscopes

A confocal microscope that captures images with a 25 mm field of view, nearly twice the area of conventional point scanners.

Capturing images of large samples such as tissues, organs and live model organisms requires both extending the detectable area of cellular responses and increasing image capture speed. The A1 HD25/A1R HD25 confocal microscope has the largest field of view (25 mm) in its field, enabling users to expand the limits of scientific research.

See more than before in confocal resolution

When combined with the Ti2-E inverted microscope, the imaging area of the A1 HD25/A1R HD25 is nearly twice the conventional FOV of 18 mm, enabling the user to obtain significantly more data by capturing more of the specimen in each shot.

Fewer total images required for large high-resolution image stitching

The large 25 mm FOV of the A1 HD25/A1R HD25 reduces both the required number of images for stitching large images and image acquisition times, enabling efficient, high-throughput imaging of even large-scale samples. The number of required images can be greatly reduced, in particular for large 3D (XYZ) image stitching.

Increase analytical throughput without compromising image resolution

The combination of a high-speed resonant scanner and large field of view forms an ideal platform for high-resolution screening assays. It dramatically reduces the time needed to analyze multiple samples and conditions.

High-speed, high-definition resonant scanner - A1R HD25

High definition imaging up to 1K x 1K

1024 x 1024 pixels enables acquisition of high-resolution, high-quality images at lower magnifications, enabling compatibility with a wide range of samples.

Low phototoxicity for live cells

High speed imaging capability up to 720 fps, in combination with a large field of view, dramatically increases imaging throughput. This scanning method reduces the exposure time of the sample to excitation light, minimizing phototoxicity and photobleaching.

For more information: https://www.microscope.healthcare.nikon.com/en_EU/products/confocal-microscopes/a1hd25-a1rhd25

Improving on Perfection.

Confocal microscopes have been commercially available now for over 25 years. How can newer iterations of a fundamentally simple instrument continue to innovate? What changes can redefine how a confocal is used, and what data can be collected? Introducing the Nikon AX/AX R Confocal Microscope System, our 10th generation point scanning confocal, giving you more of everything: Leveraging Artificial Intelligence (AI), expanding the number of colors, improving pixel density, sensitivity and speed.

These are significant additions in terms of expanding the range of experiments possible with a point scanning confocal, while increasing the usability and functionality of the instrument, all in a modular and upgradable platform.

Nikon AX is the new standard in confocal imaging.